Graduate Student, Curriculum in Genetics and Molecular Biology
B.S. University of Pittsburgh (2007)
M.S. UNC Greensboro (2013)
started in the lab March 2014
Crossovers (COs) between homologous chromosomes ensure proper meiosis I segregation; failure to produce a CO results
in nondisjunction and sterility. Although CO formation is tightly controlled, the mechanisms that implement genome-wide COs remain poorly
understood. I am interested in examining CO control mechanisms such as interference, homeostasis, and distribution using Drosophila as a model.
In a second project, I am examining the connection between chromosome dynamics, the arcitecture of the nucleus, and recombination.
Publications from research in the Sekelsky Lab
- Bloom syndrome helicase in meiosis: Pro-crossover functions of an anti-crossover protein. Bioessays 39: 1-11. DOI: 10.1002/bies.201700073.
, J. Sekelsky (2017)
- Blm helicase promotes meiotic crossover patterning and homolog disjunction. Current Biology 27: 1-5.
, K. Kohl*, S. McMahan, M. Hartmann, A. Williams, J. Sekelsky (2017)
- J.K. Holsclaw*, Genome Stability: From Virus to Human Application.
Kovalchuk and Kovalchuk, eds., Academic Press.
, and J. Sekelsky (2016)
Meiotic and Mitotic Recombination: First in Flies, in
- NIGMS T32 NRSA in Genetics appointment (2014-15).
- NRSA F31 fellowship from National Institute of Aging (2016-18).
- "Exploring the Importance of Class I Crossovers in Meiosis"
UNC-Greensboro Deptartment of Biology Seminar Series (2017).
- "Proposing a Novel Role for Centromere-Specific SMC1 in Drosophila Prophase I"
EMBO Conference on Meiosis, Hvar Croatia (Aug 2017).
- Co-Chair, Gordon-Kenan Research Seminar on Meiosis (2016).
- Organizing Committee, Triangle Fly Meeting (2015).